Group Members

Dr. Jan J. Klein
Graduate Student

AG Hecht
Department of Chemistry
Humboldt-Universität zu Berlin
Brook-Taylor-Str. 2, 12489 Berlin, Germany

Lab:      3'125
Phone: +49 (0)30 2093-7453
Email:  
kleinjan
    
chemie.hu-berlin.de
Jan Klein

Curriculum Vitae

February 5, 1982
born in Cologne, Germany
10/2002 - 10/2006
Chemistry studies (Diplom) at Technische Universität Berlin, Germany
01/2007 - 10/2007
Diplom research thesis at Humboldt-Universität zu Berlin, Germany, under the guidance of Prof. Christoph Arenz
Since 12/2007
Doctoral research at Humboldt-Universität zu Berlin, Germany, under the guidance of Prof. Stefan Hecht

RESEARCH TOPIC

"Conformationally Restricted Templates for Multivalent Recognition of Biomolecules"

Synthesis and analysis of a scaffold which enables stronger multivalent hetero-association to a biomolecule than its homo-association, thus preventing aggregation.

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J. J. Klein, S. Hecht*: "Synthesis of a New Class of Bis(thiourea)hydrazide Pseudopeptides as Potential Inhibitors of β–Sheet Aggregation" Org. Lett. 2012, 14, 330-333.
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D. Proksch, J. J. Klein, C. Arenz: "Potent Inhibition of Acid Ceramidase by Novel B-13 Analogues",  J. Lipids 2011, DOI: 10.1155/2011/971618.